A horse can die because it cannot vomit
The ring of muscle where a horse's gullet meets its stomach is a one-way valve so strong it almost never reopens, and the gullet enters at such a sharp angle that a swelling stomach only clamps it shut tighter. Food goes down and cannot come back up. So when gas or a blockage builds during a bout of colic, the stomach can stretch until it ruptures rather than empty itself, which is why colic is one of the most feared conditions in the stable.